Herb-drug interaction between Echinacea purpurea and darunavir/ritonavir in HIV-infected patients
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چکیده
منابع مشابه
Herb-drug interaction between Echinacea purpurea and etravirine in HIV-infected patients.
The aim of this open-label, fixed-sequence study was to investigate the potential of the botanical supplement Echinacea purpurea to interact with etravirine, a nonnucleoside reverse transcriptase inhibitor of HIV. Fifteen HIV-infected patients receiving antiretroviral therapy with etravirine (400 mg once daily) for at least 4 weeks were included. E. purpurea root/extract-containing capsules wer...
متن کاملHerb-drug interaction between Echinacea purpurea and darunavir/ritonavir in HIV-infected patients
The aim of this open-label, fixed-sequence study was to investigate the potential of Echinacea purpurea, a commonly used botanical supplement, to interact with the boosted protease inhibitor darunavir-ritonavir. Fifteen HIV-infected patients receiving antiretroviral therapy including darunavir-ritonavir (600/100 mg twice daily) for at least 4 weeks were included. E. purpurea root extract capsul...
متن کاملHigh-potency Anti-influenza Therapy by a Combination of Echinacea purpurea fresh herb and root tinctures
Article history: Received on: 26/10/2013 Revised on: 27/11/2013 Accepted on: 14/12/2013 Available online: 30/12/2013 The medicinal plant Echinacea purpurea (EP) contains potent antiviral and anti-inflammatory activities, which are believed to be responsible for the efficacy of such preparations in the treatment of colds and ‘flu. To determine to what extent the processes of drying, composition ...
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We describe a drug-drug interaction between coformulated lopinavir/ritonavir and itraconazole in a patient infected with human immunodeficiency virus type 1 who had disseminated histoplasmosis. Coadministration of these agents led to a strong increase in itraconazole concentrations and a decrease in concentrations of its metabolite, hydroxyitraconazole, which is equally active pharmacologically...
متن کاملCaffeic acid derivatives in dried Lamiaceae and Echinacea purpurea products
The concentrations of caffeic acid derivatives within Lamiaceae and Echinacea (herb, spice, tea, and dietary supplement forms) readily available in the US marketplace (n = 72) were determined. After the first identification of chicoric acid in Ocimum basilicum (basil), the extent to which chicoric acid could be found within the family Lamiaceae was investigated. The dominant phenolic acid in al...
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ژورنال
عنوان ژورنال: Journal of the International AIDS Society
سال: 2010
ISSN: 1758-2652
DOI: 10.1186/1758-2652-13-s4-p187